For safety and efficacy, one needs to follow the usage guidelines not to step out of bounds while using methylformamide. In industrial or laboratory settings, proper gloves, goggles, and lab coats must be worn as personal protective equipment (PPE). It must be utilized in places with sufficient ventilation so as not to inhale any of its vapors. The amount used must be very accurately measured based on the set process limitations. When using it in chemical reactions, specific conditions such as the temperature and duration of the reaction must be controlled if one is to achieve set targets. Steps must be followed in the right manner after use to ensure proper disposal protocols are adhered to
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